Side Effects and Complications of Bone Marrow Transplant

Among the two types of transplants, we prefer the autologous transplant because this type will produce the best match. In the autologous transplant, the donor is a close relative such as a brother or sister, or a parent. The chances of having a 100% match is not possible in the majority of the cases but in the autologous transplant, the chances are more.

Donors outside the family

In the allogeneic transplant, the patient receives the stem cells from a person outside the family. This includes a distant relative (person not inside the primary family) or a colleague or well-wisher. The immune system of the patient will reject the donor cells if there is no match. Usually, we do the HLA typing for the tissues and blood.

HLA stands for Human Leukocyte Antigen that stands for a series of proteins. These proteins exist on the surface of the cells in your body. According to the genetic definition of these genes, you will be able to check whether the donor is a good match or not. When the match is good, it will reduce the risk of GVHD – Graft versus Host Disease – and so one must check this first.

Good treatment facility in India

You can get treated at the best allogenic bone marrow transplant hospitals in India. This will improve the chances of recovery to a great extent. India has the best facilities for treatment and the cost is low compared to that of foreign countries. The cost of treatment in foreign countries is in the range of 500, 00,000 INR while the cost in India is about 7, 00,000 INR.

Side effects are normal

Though the transplant goes well, the patient will experience some side effects. You might see these symptoms when you undergo a transplant:

  • Chest pain
  • Hives
  • Drop in blood pressure
  • Nausea
  • Fevers and chills
  • Pain
  • Funny taste in the mouth
  • Shortness of breath

They do Tandem transplants when the patient has testicular cancer or multiple myeloma. In this, they do two transplants one after the other. The patient gets high-dose chemotherapy one after the other and we follow each one by a transplant of the stem cells. They collect the needed stem cells before the first high-dose chemotherapy and we use half of them for each treatment. They give these two courses of chemotherapy within six months of each other. They wait until the patient recovers from the first chemo treatment and then give him the second one.

Be prepared for complications

Development of complications is possible when you undergo transplant of the bone marrow. This development depends on a set of conditions that include the following:

  1. Age
  2. Health in general
  3. The disease that afflicts you
  4. Previous chemotherapy or radiation
  5. Type of bone marrow you got
  6. Degree of match

Getting prepared for the transplant surgery involves many things. Check the list of best allogenic bone marrow transplant hospital in India and fix an appointment. The doctor will examine you and advise you about the best course of action. This might involve going on a diet, making changes to your lifestyle (such as stopping smoking), stopping some medication and starting a few others, and so on.


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